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Welcome to Uptown Drug & Gift Shop, a family‐run business established in 1945. The proprietors are Jo Ann and Jerry Shapiro, who purchased the store from Jerry’s parents in 1969. For twenty‐seven years, the store was located in the mid‐Wilshire area. Seeing the rebirth of downtown L.A., we decided to move our business there in August of 2004.

At Uptown Drug, you’ll receive the personal attention you deserve. We treat our customers as we would our family! Our pharmacy offers comprehensive medication review through an assessment of all of a patient’s medications. The goal is to optimize therapeutic regimens, improve medication compliance, and enhance therapeutic outcomes of the medications.

We gladly perform health screenings, offer diabetic services, give immunizations, compound those special need prescriptions, and maintain a quality stock of over‐the‐counter drugs, sundries, and dietary supplements. We deliver to a widespread area for a small fee or no charge in some cases. If you happen to live, work, or are staying at a hotel in downtown, please call us and we'll make arrangements to get your medicine to you promptly.

Our gift shop is full of interesting gifts hand‐selected for you. We carry a large selection of half‐priced greeting cards, baby gifts, Nao by Lladro, jewelry, plush gifts, men's executive gifts, cosmetics, and travel items. Remember that our selection changes regularly, so you'll always find something new for a gift or personal indulgence.

We look forward to serving your needs for many years to come.

p: (213) 612-4300

f: (213) 612-4313

  • Monday: 8:30am5:30pm
  • Tuesday: 8:30am5:30pm
  • Wednesday: 8:30am5:30pm
  • Thursday: 8:30am5:30pm
  • Friday: 8:30am5:30pm
  • Saturday: Closed
  • Sunday: Closed
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